Category: Uncategorized

ATP is "continuously recycled in organisms: the human body, which on average contains only 250 grams (8.8 oz) of ATP, turns over its own body weight equivalent in ATP each day." https://lnkd.in/eStagA3 View in LinkedIn

THE CORE MACHINERY. "When a strong opposing torque is imposed, the gamma shaft rotates in the opposite direction and drives the F1-motor to synthesize ATP." https://lnkd.in/eYcwEF7 View in LinkedIn

MOLECULAR CURRENCY. "Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer. Metabolic processes that use ATP as an energy source convert it back into its precursors." https://lnkd.in/eStagA3 View in LinkedIn

THE CORE MACHINERY "is the subcomplex F1-motor (F1-ATPase) and performs the reversible mechanochemical coupling. The isolated F1-motor hydrolyzes ATP, which is accompanied by unidirectional rotation of its central gamma shaft." https://lnkd.in/eYcwEF7 View in LinkedIn

ANOTHER BIO-AWARD. "The synthesis of ATP is undoubtedly the most important phenomenon that occurs in living organisms." A separate series on ATP will follow ATP synthase. https://lnkd.in/eaMvYSf View in LinkedIn

TEXT OF ATP SYNTHASE FUNCTIONALITY. This is a thoroughly granular description of one ATP synthase, with details of the molecular pockets, architecture of the peripheral stalks and their subunits. This gives a detailed picture of the sheer complexity of this molecule. https://lnkd.in/eERctEF View in LinkedIn

1997 NOBEL PRIZE for Chemistry went to Dr John E. Walker (Medical Research Council's Laboratory of Molecular Biology (LMB) at Cambridge); Dr Paul D. Boyer (University of California at Los Angeles); and Dr Jens C. Skou (Aarhus University in Denmark) for their groundbreaking studies of ATP synthase. https://lnkd.in/eAtWnVk View in LinkedIn

9,000 RPM MINI-MOTOR. "During ATP synthesis, the central rotor turns...about 150 times every second. In order to provide energy to sustain our lives, every day, each one of us produces a quantity of ATP by this mechanism that is approximately equal to our body weight." A number of commercial motors operate at 9,000 RPM. https://lnkd.in/eu4ehmH View in LinkedIn

ATP SYNTHASE, which makes the all-important ATP, has been called the "molecular engine of life" as well as paradoxically being "an efficient death machine." This molecule ranks along with DNA, chlorophyll, and a number of other molecules, as one the heavyweight champions of life on planet earth. https://lnkd.in/eNs9_jp View in LinkedIn

TWO MOTORS AND A ROTOR. "One motor generates rotation by consuming energy derived from oxidative metabolism or photosynthesis; the other uses energy transmitted by the rotor to put ATP molecules together from their building blocks, ADP and phosphate." https://lnkd.in/eahb8Gv View in LinkedIn