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RNA AS SOCIAL NETWORK. "In this world of life processes actively dominated by RNA, DNA is increasingly cast in the role of the “house” of genetic information storage, whereas the interacting RNAs seem to be the “social network” within this house." https://lnkd.in/eUYvi8e View in LinkedIn

RNA AGENTS AND PROTEIN CODING. "It now seems plausible that the basic coding of proteins and their variable regulations (conserved in DNA) are the collective results of an abundance of complementary RNA agents." https://lnkd.in/eUYvi8e View in LinkedIn

NATURAL SELECTION IN RNA CONSORTIA. "Whereas the single stem-loop emergence seems to not be subjected to selection processes, the consortia that are built with these tools are subjected to selection processes." https://lnkd.in/eUYvi8e View in LinkedIn

STEM LOOPS. "They are not only remnants of the ancient RNA world but ongoing infection-derived modular tools for new cellular needs, that is, “domesticated” consortia of interacting RNA agents such as viruses, mobile genetic elements, and noncoding RNAs." https://lnkd.in/eUYvi8e View in LinkedIn

RNA WORLD AGENTS. "These compatible stem loops not only comprise the agents of the current RNA world but also include all forms of RNA viruses. This means the stem-loop tool—with its base-pairing and nonpairing composition—is relevant to all agents of the current RNA world being active in cellular genomes after transcription." https://lnkd.in/eUYvi8e View in LinkedIn

SHARED MOTIFS. "Each RNA nucleotide of any natural RNA sequence is part of one of these secondary structure motifs: stem, loop, bulge, junction or end, or another unpaired region. This means that the composition of RNA bases follows the stem-loop architecture as an appropriate tool, to store information and build more complex ensembles that together act catalytically as ribozymes." https://lnkd.in/eUYvi8e View in LinkedIn

COEVOLUTION. "A rather astonishing conclusion of these facts is that randomly associated RNAs that have no evolutionary history show the same structure-dependent compositional bias as ribosomal RNAs. This means that the differences do not depend on selection processes but on the overall composition of the RNA consortium." https://lnkd.in/eUYvi8e View in LinkedIn

SEQUENCE AND MEANING. "The most crucial questions are: do DNA sequences contain a hidden deep grammar structure that varies according to the meaning and context of environmental insults; do DNA sequences match with high fidelity environmental circumstances that led to epigenetic markings and memory? If yes, this would then mean that the identical DNA sequence may have various- even contradictory-meanings. In fact, this scenario is emerging as true." https://lnkd.in/eG_TcWz View in LinkedIn

"ALU ELEMENTS alone are estimated to have inserted into 75% of all human genes." https://lnkd.in/eUYvi8e View in LinkedIn

PARASITE COMPETITION FOR HOSTS. "The presence of one parasite might prevent infection or manipulation by another parasite. Wolbachia, for example, has been reported to reduce or increase the susceptibility of its host to virus infections." https://lnkd.in/e2g9KSe View in LinkedIn