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China's giant space telescope starts search for alien life View in LinkedIn

"EARLY LIFE environmental influences have a profound impact on the organism's later development, structure, and function. This phenomenon is called “developmental programming"...exerts effects that impact on structure and function of organs that, in some cases, will persist throughout life. One such environmental factor is the gut microbiota that, because of an evolutionary process, has adapted to coexist in commensal or symbiotic relationship with mammals." https://lnkd.in/e7Pmtsp View in LinkedIn

CONUNDRUM. "For darwinism the CNGs are a conundrum — highly conserved sequences with no known function. Well, they must have a function, but what is it? And how could they have been gradually composed, and yet so tightly constrained?" (CNG = conserved nongenic (non-gene).sequences). https://lnkd.in/eFvUyrd View in LinkedIn

MICROBES DRIVE MANY HUMAN ORGANS. "Immediately after birth, the newborn organism is rapidly and densely populated with complex forms of indigenous microbes. This process has been shown to contribute to developmental programming of epithelial barrier function, gut homeostasis, and angiogenesis, as well as the innate and host adaptive immune function...gut microbiota have systemic effects on liver function." https://lnkd.in/e7Pmtsp View in LinkedIn

NUMEROUS. "Another surprise is the high number of the CNGs. Extrapolating from the human chromosome analyzed, the geneticists estimate that humans have over 65,000 of them, about twice the estimated number of human genes. Another multispecies comparison that employed different methods found a similar number." (CNG = conserved nongenic (non-gene).sequences). https://lnkd.in/eFvUyrd View in LinkedIn

GUT MICROBES AFFECT BRAIN. "Here, we report that colonization by gut microbiota impacts mammalian brain development and subsequent adult behavior...our results suggest that the microbial colonization process initiates signaling mechanisms that affect neuronal circuits involved in motor control and anxiety behavior." https://lnkd.in/e7Pmtsp View in LinkedIn

TWIST ON SELECTION. "A selective constraint "is selective pressure that determines and limits the number of neutral/beneficial mutations that can take place. The more constrained a locus is under selection, the easier it is to generate deleterious mutations and the harder it is to generate beneficial ones; this can be reflected in low substitution rates at such loci in populations with time." https://lnkd.in/e6Dxb5h View in LinkedIn

SONG OF DARWIN. "The more I study nature, the more I become impressed […] that the contrivances and beautiful adaptations [acquired through natural selection] transcend in an incomparable degree [those] which the most fertile imagination of the most imaginative man could suggest with unlimited time at his disposal." https://lnkd.in/eykUy37 View in LinkedIn

FRAGMENT FROM NATURE follows on from the extensive subject about a range of parasites profoundly that affect host behavior and brain activity. We are also hosts to symbiotic gut bacteria, the gut microbiome, that also has profound effects on our brain, mood and development. These gut symbionts keep pathological bacteria under control. When the ecological balance is disturbed, the pathological bacteria gain a dominant position and cause illness. View in LinkedIn

THE QUESTION. "Why does an onion require five times more of it (the genome) than a human? " http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn