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EU drops law to limit cancer-linked chemical in food after industry complaint View in LinkedIn

JUVENILE HORMONE TRIGGER. "In insects, transition from juvenile to adult stages is triggered by the decline of the juvenile hormone, but the molecular mechanisms underlying the dramatic morphological and physiological changes remain poorly understood." http://www.pnas.org/content/111/19/7024.full View in LinkedIn

NOT REDUNDANCY. "In Lepidoptera, the coexistence of autophagic and apoptotic features has been frequently described in many organs that die during metamorphosis. This copresence of autophagic and apoptotic characteristics within the same organ does not seem to represent mere redundancy and adds evidence to the hypothesis that there is an overlap in the regulatory pathways of autophagy and apoptosis." https://lnkd.in/eED2fPx View in LinkedIn

SELF-DIGESTION. "It became rapidly clear that homologs of most of the genes that belong to the autophagic pathway are present in the silkworm genome. The demise of larval organs in holometabolous insects...requires both autophagy and apoptosis." https://lnkd.in/eED2fPx View in LinkedIn

TWO REMODELING MECHANISMS. "It has been demonstrated that larval organs in holometabolous insects degenerate mainly through apoptosis and autophagy." https://lnkd.in/eED2fPx View in LinkedIn

COMPLETE DEGENERATION. "Metamorphosis represents a critical phase in the development of holometabolous insects, during which the larval body is completely reorganized: in fact, most of the larval organs undergo remodeling or completely degenerate before the final structure of the adult insect is rebuilt." https://lnkd.in/eED2fPx View in LinkedIn

SONG OF DARWIN. "The more I study nature, the more I become impressed […] that the contrivances and beautiful adaptations [acquired through natural selection] transcend in an incomparable degree [those] which the most fertile imagination of the most imaginative man could suggest with unlimited time at his disposal." https://lnkd.in/eykUy37 View in LinkedIn

FRAGMENT FROM NATURE continues for the second weekend on the subject of insect metamorphosis. Genetic triggers launch a series of biochemical methods to digest the cells in the chrysalis and then remodel the ingredients without waste into new cells with new forms and functions, all the while permitting this soup of a creature to continue to breathe and stay alive. The how does not exceed the why in this iconic and mysterious transition. View in LinkedIn

MASTER FACTOR. "Our study has demonstrated that, despite the evolutionary distance and the differences in the developmental strategies of reaching adulthood, E93 is the universal adult specifier that acts as the “master factor” of adult metamorphosis in hemimetabolous and holometabolous insects." (E93= a transcription factor). http://www.pnas.org/content/111/19/7024.full View in LinkedIn

VESTIGIAL CONSEQUENCE. "Eukaryotic transcription is inherently noisy." When a completely foreign metabolic pathway is bolted-on, no surprise. http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn