Category: Uncategorized

COUPLING. "A common theme that has emerged from the study of mRNA synthesis is that various steps in RNA synthesis and processing are biochemically coupled. In other words, cellular machineries that participate in one biochemical activity also promote subsequent steps." http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn

COUNTER-ARGUMENT. "Although pervasive transcription has been used as an argument against junk DNA, it is in fact entirely in line with the idea that intergenic regions are evolving under little-to-no constraint, especially when one considers that this intergenic transcription is unstable." http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn

INTERGENIC RNA. "These data indicate that the majority of intergenic RNAs are degraded almost immediately after transcription. Consistent with this idea, the level of intergenic transcripts increase when RNA degradation machinery is inhibited." http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn

A 100% different perspective... http://qz.com/804022/health-benefits-japanese-forest-bathing/ View in LinkedIn

NUCLEAR HOME. "Strikingly, when one examines the steady state level of polyadenylated RNA, very little maps to intergenic regions. In fact, when one eliminates the ∼9,000 transcript species that are thought to be derived from conserved lncRNA, then most of the annotated noncoding polyadenylated RNAs are present at levels below one copy per cell and are found exclusively in the nucleus." (LncRNAs = long non-coding RNAs). http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004351 View in LinkedIn

POLYADENYLATED RNA. "Polyadenylation is an important post-transcriptional modification of prokaryotic, eukaryotic and organellar RNA." https://lnkd.in/eaCHGGt View in LinkedIn

EMERGING PICTURE. "Despite the incompleteness of lncRNA annotations, it is nonetheless clear that lncRNAs are frequently present within non-coding regions of the genome known to be functional." (LncRNAs = long non-coding RNAs). https://lnkd.in/e9BHyYj View in LinkedIn

TALUS & CALCANEUS. "A key event in transforming the therapsid foot into a mammalian one was the superimposition of the talus upon the calcaneus. This introduced a new flexibility into the foot by providing for inversion and eversion at the subtalar joint complex." https://lnkd.in/et2pUax View in LinkedIn

THE NEXT SECTION deals with major evolutionary transitions. These events have shaped life on earth, but our understanding of them is, as usual, rather scant. However, this is a very interesting topic, and some great thinkers have applied themselves to the topic. View in LinkedIn

PASSING THROUGH. "It seems quite clear that the anatomy of living marsupials (metatherians) gives a good indication of the structure of those advanced early Cretaceous therians from which the first placentals (eutherians) evolved. One might say, as has Lillegraven (1974) that the eutherians passed through a metatherian grade." https://lnkd.in/et2pUax View in LinkedIn