SEVEN PIECES of new data accumulated in the last two decades change prevailing paradigms in molecular biology. In summary: #1. Mobile genetic elements; #2. Reverse genetics; #3. Non-coding DNA and RNA is not junk; #4. Endosymbiosis of third domain; #5. Role of Viruses in evolution; #6. Epigenetics; #7. communication between cells and molecules. Combined together, these now constitute a new hypothesis about developmental processes, evolution, and molecular biology.