linkedin post 2017-04-15 05:55:40

OTHER FUNCTIONAL MUTATIONS. “As changes in the coding region, especially of transcription factors, can cause downstream changes within a GRN that result in spatial and/or temporal alterations in gene expression, a mutation does not have to be in a regulatory region to cause a heritable regulatory change. Thus, while regulatory changes in gene expression are a major factor in evodevo, these changes may be caused by different types of functional mutations.” (GRN = gene regulatory network).

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