TRUNK EPITOPE SELECTION. “Phylogenetic analysis of H3N2 influenza has shown that putative epitope sites of the HA protein evolve approximately 3.5 times faster on the trunk of the phylogeny than on side branches. This suggests that viruses possessing mutations to these exposed sites benefit from positive selection and are more likely than viruses lacking such mutations to take over the influenza population.”
https://lnkd.in/dDjCWve
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022