SUBSET TRANS PATH. “In contrast, trans epigenetic signals are maintained by soluble molecules such as transcription factors or small RNAs (sRNAs) acting in feedback loops of self regulation of own expression level. Recently it has been argued that prions could also represent a kind of epigenetic inheritance/paramutation-like phenomenon not based on nucleic acid but on the protein folding, resulting in different activity.”
https://lnkd.in/daR66WW