COMPLEX ASSEMBLY. “The HK97 assembly pathway begins with self-assembly of the capsid protein, gp5, into pentamers and hexamers. A protease, gp4, cleaves gp5 at its N-terminus. Attachment of a portal protein, gp3, coupled with conformational changes leads to formation of a prohead or procapsid structure. Further conformational changes and crosslinking of gp5 monomers comprise further capsid maturation and lead to formation of a mature phage head.”
https://lnkd.in/d9B2fAQ
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022