SELFISH BRAIN. “The presented model includes a newly discovered ‘principle of balance’ of how pairs of high and low-affinity receptors can originate setpoints in biological systems. In this ‘Selfish Brain Theory’, the neocortex and limbic system play a central role in the pathogenesis of diseases such as anorexia nervosa and obesity.”
http://www.sciencedirect.com/science/article/pii/S0149763404000259