ORGANS ON A CHIP for drug screening are an important advance but more so when the organ is from a patient tissue. That said, this kind of testing is no surrogate for the whole organism, because drug actives bind proteins to different amounts, get degraded by different systems, all contributing to PK and PD differences that can still give a new drug candidate a thumbs down. ”
“A more human and more tissue relevant screening mode is always a step forward.
http://lnkd.in/namzqe
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022