“ACTIVATION in temperature-sensitive TRP channels is characterized by very large enthalpy changes that are compensated by similarly large entropy changes. For example, enthalpy changes of about 100 kcal/mol, 200 kcal/mol, and 60 kcal/mol are involved in the opening of TRPV1, TRPV2, and TRPM8, respectively.”
https://lnkd.in/eZQCjnY