ROGUE PROTEIN ISOFORMS. “The best-known attribute of the prion protein (PrP) is its tendency to misfold into a rogue isoform. Neurodegeneration in prion disease is often seen as a consequence of abnormal PrP function yet, amazingly little is known about the normal, physiological role of PrP. In particular, the absence of obvious phenotypes in PrP knockout mice has prevented scientists from answering this important question.”
https://lnkd.in/eBQR5Bd
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022