COMPLEX BEINGS RESIST INNOVATION. “A primordial cell harbouring a small group of genes can potentially gain a lot by adding new genes to its repertoire; but a more sophisticated cell with hundreds or thousands of genes risks imbalancing an intricate genome fine-tuned by a longer period of natural selection. So, complex eukaryotic cells evolved new ways to protect their DNA and expunge genetic invaders.”
https://aeon.co/essays/genes-that-jump-species-does-this-shake-the-tree-of-life