APOPTOSOME. “In many cells, the apoptosome is dispensable for stress-induced apoptosis. Since the level of total caspase activity is markedly lower in its absence, the apoptosome must be an amplifier of the caspase cascade rather than a critical initiator of it. Apparently the amplification is more important for ensuring the death of certain cell types (e.g., neuronal precursors) than others (e.g., lymphocytes).”
https://lnkd.in/er7D9PK
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022