TOXIC REACTIVE OXYGEN. “Extracellular ATP and the P2X7R are also important in inflammasome activation as triggers of ROS generation. Many agents reported to drive NLRP3 activation via ROS generation are also potent triggers of ATP release (Aβ, hyperglycemia, skin irritants, infections, ultraviolet light).” (ROS = toxic reactive oxygen species from mitochondria).
https://lnkd.in/eNNPn5D
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022