TOXIN RESISTANCE. “The muscular nicotinic cholinergic receptor (nAChR), targeted by snake α-neurotoxins, has evolved in some venom-resistant mammals to no longer bind these toxins. Through phylogenetic analysis of mammalian nAChR sequences, we show that honey badgers, hedgehogs, and pigs have independently acquired functionally equivalent amino acid replacements in the toxin-binding site of this receptor.”
http://www.sciencedirect.com/science/article/pii/S0041010115000690
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022