ENDONUCLEASE PROOFREADING. “Cellular DNA replication complexes contain exonuclease activities that come into play when an incorrect base has been incorporated onto the nascent DNA strand. Studies with Escherichia coli indicate that exonuclease proofreading removes about 99.9% of the accidental misincorporations from the nascent strand.”
http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2014.271130/full