GRAND SYNTHESIS. “Shapiro integrates advances in symbiogenesis, epigenetics, and saltationism into a unified approach that views evolutionary change as an active cell process, regulated epigenetically and capable of making rapid large changes by horizontal DNA transfer, inter-specific hybridization, whole genome doubling, symbiogenesis, or massive genome restructuring.” (Regarding (James A. Shapiro, Evolution: A View from the 21st Century).
http://www.thethirdwayofevolution.com/people/view/james-a-shapiro