ISOFORM DIVERSITY. “The ENCODE project team observed that human genes do not follow a minimalistic isoform expression strategy; instead each gene simultaneously produces up to 10 to 12 isoforms. In contrast, Brown et al., observed that in Drosophila, most genes have relatively few isoforms. In fact, 42% of Drosophila genes encode only a single transcript isoform, whereas in mammals, 95% of genes have multiple expressed isoforms.”
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