FOLDS AND DISTANT FAMILIES. “By analyzing protein sequences we were able to identify EFs shared by seemingly unrelated protein superfamilies and folds and to unravel evolutionary relations between them. Binding and metabolic processing of the metal- and nucleotide-containing cofactors and ligands are among the most abundant ancient EFs that became indispensable in many natural enzymes.” (EFs = elementary functions). https://lnkd.in/dwbv2VX
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022