VITAMIN SECRETION. “Adrenal glands are known to have very high concentrations of vitamin C and Albert Szent-Györgyi first isolated it from ox adrenals. Human adrenal glands in vivo secrete vitamin C in response to ACTH which stimulates adrenal cortex to produce the essential hormone cortisol. Vitamin C secretion is rapid, starting and ending within minutes of ACTH administration in humans, and precedes cortisol secretion. In animals, the testes and ovary also secrete ascorbate. Ascorbate secretion also occurs in the stomach.”
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