linkedin post 2017-08-20 05:21:11

CENTRAL STRUCTURAL UNIT. “For many (if not all) bacterial and archaeal tailed viruses and eukaryotic Herpesvirdae the HK97-fold serves as the major architectural element in icosahedral capsid formation while still enabling the conformational flexibility required during assembly and maturation. Auxiliary proteins or Δ-domains strictly control assembly of multiple, identical, HK97-like subunits into procapsids with specific icosahedral symmetries, rather than aberrant non-icosahedral structures.”

http://www.sciencedirect.com/science/article/pii/S0042682215001920

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