linkedin post 2017-08-20 05:34:33

CHAINMAIL AND CEMENT. “In HK97 itself, the intersubunit contacts are reinforced by a post-assembly covalent linkage—an isopeptide bond between adjacent gp5 subunits, so positioned that the entire capsid is topologically interlinked in a ‘chainmail’ arrangement. In other cases, such as bacteriophage λ, the non-covalent interactions between the subunits are reinforced by an additional ‘cement’ protein, which binds on the outer surface of the capsid at positions close to those of the isopeptide bonds in HK97.”

https://elifesciences.org/content/2/e01299

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