MULTILAYERED CAKE. “A major challenge in pathobiome research will thus be to develop and apply concepts and approaches of microbial ecology and evolutionary biology to pathogens and the microbial communities in which they exist. A peculiarity of pathobiomes is that they involve multiple complex interactions within microbial communities, the host and the environment, and are subject to strong selection pressures that sometimes lead to extreme adaptations (e.g., species which have recently become intracellular parasites).”
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