linkedin post 2018-06-09 05:09:23

GREAT UNKNOWN. “More than 25,000 bacterial and archaeal host genomes are available in NCBI RefSeq (January 2015), whereas only 1,531 of their viruses were entirely sequenced and most (86%) of these derive from only 3 of 61 known host phyla. Thus, although advances in high-throughput sequencing expand the bounds of viral sequence space, these data sets are dominated by uncharacterized sequences (usually 60–95%), termed ‘viral dark matter’.”

https://elifesciences.org/content/4/e08490

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