MUTATIONS SHELTERED. “When RNAs function through their 2D or 3D structural conformations, mutations are often tolerated provided that they maintain complementary base pairing—an occurrence termed covariation, which is a bona fide indication of evolutionary selection on RNA structure.”
http://nar.oxfordjournals.org/content/early/2013/07/11/nar.gkt596.full
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022