BACK TO CHROMATIN. “Telomere-mediated activation of the DNA damage response appears to be intimately linked to the chromatin structure. Specifically, it was shown that chronic DNA damage from the processed telomeres also affects histone expression leading to their depletion and to the depletion of the central histone chaperones.”
http://journal.frontiersin.org/article/10.3389/fgene.2013.00136/full
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022