STAR ASSEMBLY. “The assembly of a wedge had been shown to follow a strictly ordered sequence. First, an initial complex is formed by a monomer of gp7 and a trimer of gp10, followed sequentially by binding of a dimer of gp8 and a dimer of gp6 to the complex. In the absence of a central hub, at least five proteins (gp7, gp10, gp8, gp6, and gp53) are required for assembly of wedges in vitro into a star-shaped, low-energy baseplate-like structure.”
http://www.pnas.org/content/113/10/2654.full
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022