ERROR RATES. “We have recently developed a novel method that allows us to estimate transcription error rates and the degree to which these vary among eukaryotic lineages. Remarkably, error rates at this level are typically >1000x those at the level of genome replication. The implication is that >1% of transcripts typically contain an erroneous base.”
http://www.bio.indiana.edu/faculty/directory/profile.php?person=milynch