DIAGNOSTIC SOLUTION. “To overcome this limitation an experimental approach was developed that dramatically reduces sequencing errors.The basic premise of this method, called Circular Sequencing (or CirSeq). Using this approach, we are now able to estimate changes in mutation frequency of variants that exist in the population at very low levels. This opens an opportunity to determine fitness landscape at single nucleotide resolution.”
http://www.sciencedirect.com/science/article/pii/S0042682215001580
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022