linkedin post 2019-05-21 04:56:36

SIMPLICITY TO COMPLEXITY (AGAIN). “Our genomes encode a limited number of antibody genes, which are insufficient to generate antibodies against the wide variety of foreign pathogens encountered from the external environment. SHM enables our immune system to expand the limited diversity encoded within our genomes to the billions of antibody specificities required to defend ourselves against external pathogens.” (SHM = somatic hypermutation).

https://lnkd.in/dQ6QXSG

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