HUB GROUPINGS. “Numerous studies have broken the hub proteins into two separate categories: those that form simultaneous stable complexes with their many interaction partners (party/multi-interface/stable hubs), and those that interact transiently with their partners at separate times (date/singlish-interface/transient hubs). Of these two hub types, only the transiently interacting hubs were found to be enriched in disorder.”
http://www.biochemj.org/content/454/3/361?sa=X&ved=0CDkQ9QEwEWoVChMIzdjAo5n2xgIVovRyCh0HSAum