linkedin post 2019-10-19 07:14:42

POLYMORPHIC WORDS. “A major advantage of using peptides for intercellular crosstalk is their polymorphism. A single amino acid exchange or modification can easily result in complete loss of binding capability at specific cell surface receptors. The specificity of crosstalk, thus, seems to be often mediated by the polymorphic small secreted protein/peptide ligands expressed by individual cell types. Studies to date have initiated the identification of small proteins that act as signaling ligands, together with some of their functions.”

http://www.sciencedirect.com/science/article/pii/S1674205214608996

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