linkedin post 2020-02-08 06:06:19

METHODOLOGICAL LIMITATIONS. “The idea of a “Nuclear Receptor” that could directly translate simple chemical changes into distinct physiologic effects persisted for several decades, but the fundamental nature of this receptor, its means for recognizing specific chemical ligands, its mode of interaction with the genome, and its mechanism for control of gene transcription were all beyond the limits of classic biochemical analysis.”

https://lnkd.in/dXjCCgQ

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