linkedin post 2020-05-30 05:26:55

SELECTION FOR FUNCTIONALITY. “McConkey predicted that most cellular proteins interact extensively and transiently with other macromolecules to produce a functional ‘quinary’ structure that constrains protein evolution by accommodating only those mutations with no functional implications, i.e. noninteracting sites.”

http://onlinelibrary.wiley.com/doi/10.1111/febs.13744/full

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