STASIS BY NECESSITY. “But if the function of a protein is restricted to one module, and the connections of that module to other modules are through individual proteins, it will be much easier to modify, make and prune connections to other modules. This idea is supported by the analogous observation that proteins that interact with many other proteins, such as histones, actin and tubulin, have changed very little during evolution, and by theoretical arguments that proteins are difficult to evolve once they are participating in many different interactions.”
https://www.nature.com/articles/35011540
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022