FAIL-SAFE DEVICES. “DNA replication involves a fail-safe system of error correction, with proofreading by the DNA polymerase backed up by a mismatch repair process that removes incorrect bases after the polymerase has moved on. A failure in either process still allows cells to make viable progeny, but simultaneous failure of both is lethal. In both biological and man-made systems, reducing the frequency of failure often requires an enormous increase in the complexity of circuits.”
https://www.nature.com/articles/35011540