TESTING THE HYPOTHESIS. “This was first explored by combining water samples with lactisole as an established TAS1R2/TAS1R3 inhibitor. Using the two-alternative forced-choice (2AFC) method, in which the participant must choose between two samples, 18 out of 25 panelists chose pure D2O as sweeter than D2O + 0.9 mM lactisole solution (p < 0.05, Fig. 4a).”
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