MOLECULAR DOSE RESPONSE. “Next, TAS1R2/TAS1R3 receptor along with the chimeric Gα16gust44 subunit were transiently expressed, and the functionality was illustrated by dose-dependent response to D-glucose (Fig. 6c). Finally, and in agreement with calcium imaging, we found that 10% D2O activated these cells. Activation by 100% D2O was even more pronounced (Fig. 6d).”
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