PATHWAYS. “Several cellular and molecular mechanisms are involved in inflammaging, including cellular senescence, mitochondrial dysfunction, defective autophagy and mitophagy, activation of the inflammasome, dysregulation of the ubiquitin–proteasome system, activation of the DNA damage response and dysbiosis (changes in the composition of the host microbiota).”
https://www.nature.com/articles/s41574-018-0059-4