HITCHHIKING MUTATIONS. “Indeed, both mutation-rate scenarios have been observed in an E. coli population in the LTEE. After thousands of generations, a mutation in the nucleoside triphosphate pyrophosphohydrolase gene (mutT) that caused a ~150-fold increase in mutation rates spread through the population, presumably by hitchhiking with one or more beneficial mutations.”
https://www.nature.com/articles/nrg3564