GENETIC SUSCEPTIBILITY. “Early landmark studies have shown that mice carrying mutations in individual genes related to the circadian clock (mutation of period 2 (Per2m/m); heterozygous ablation of aryl hydrocarbon receptor nuclear translocator–like protein 1 (Arntl) (Bmal1+/–); and double-null cryptochrome 1 (Cry1) and Cry2 (Cry1/2–/–)) are more susceptible to lymphoma, and when irradiated, these mutant mice have increased rates of lymphoma and hepatocellular carcinoma.”
https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022