EPIGENETIC FACTORS. “Epidemiological studies indicate that disruption of circadian rhythms in humans is associated to increased cancer risk (see above). In addition, pilot data now suggest that shift work can also regulate the epigenetic landscape, which could likely be a mechanism by which circadian gene expression is altered.”
https://www.nature.com/articles/s41591-018-0271-8?fbclid=IwAR01C2Z4J5lxVYDLhxIb9dPb3fhNSZSxwimZvhHaJ4n3-nVPpkt2PNqoukk