Month: September 2022

NOT LINEAR. "These identity networks cannot be teased apart to define a single and linear logic as is currently accepted for individual fittest type selection." https://lnkd.in/eWydwab View in LinkedIn

DNA VIRUS-DRIVEN EVOLUTION. "Prokaryotic genetic changes are mostly driven by dsDNA parasites (virus and plasmids)." https://lnkd.in/eWydwab View in LinkedIn

RNA VIRUS-DRIVEN EVOLUTION. "In eukaryotes, RNA agents (retroviruses and retroposons) are much more diverse, numerous and dynamic and are providing multiple levels of regulatory complexity. We have recently come to realize that transcription of such retroposon sequence (previously considered junk) is abundant and often produces non-coding RNAs, all being part of stem-loop regions." https://lnkd.in/eWydwab View in LinkedIn

"RETROVIRAL NETWORKS Regulate Evolution and Development. Various small non-coding RNAs participate in ‘multi-task’ networks and such RNAs tend to be transcribed from ‘junk’ retroposons." https://lnkd.in/eWydwab View in LinkedIn

GENOME EDITORS. "In terms of active editors of the human genome, there are about 330,000 solo LTRs each of which must have initially corresponded to an intact ERV (*10 kb) subsequently lost by deletion. This means that 3.3 gB of human DNA (current size of our genome) was once retrovirus during our evolution." (LTR = long terminal repeats, from retroviruses; ERV = endogenous retroviruses). https://lnkd.in/eWydwab View in LinkedIn

NEW GENETIC REGULATORS. "LTRs are highly involved in the emergence of new regulatory networks, such as the origin of the placenta" and other cellular systems. (LTR = long terminal repeats, from retroviruses). https://lnkd.in/eWydwab View in LinkedIn

FOREIGN GENOME EDITING. "There is growing evidence that natural genome-editing competences of viruses are essential for the evolution of the eukaryotic nucleus, the adaptive immune system and the placental mammals." https://lnkd.in/e-pJFM6 View in LinkedIn

RNA RIBOSOME NETWORKS. "Recently, there has been an accumulation of experimental evidence that RNA ribozymes do act and emerge from collectives that can also form networks." https://lnkd.in/eWydwab View in LinkedIn

ADDICTION MODULES. "Infected host organisms are the habitats in which such formerly competing agent groups (‘‘Gangen’’) now unify in addiction modules, which provide group identity such as TA, RM, and ID modules." https://lnkd.in/eWydwab View in LinkedIn

PROTECTIVE MODULES. "All of the former competing groups become unified into stable/unstable modules that are counter-regulated, to provide immunity and memory systems, such as VDJ and CRISPRS/Cas, against related genetic parasites for the host." https://lnkd.in/eWydwab View in LinkedIn