Month: September 2022

“SELF-ORGANIZATION BY SELECTION requires dynamic diversity (constitutional and/or morphological) on which to operate. This is made possible by the implementation of CDC responding to the pressure of either internal or external factors. Selection has an implicit information content. It is also truly a supramolecular process, because it occurs in relation to interactions with surroundings (which may be either the medium or a more or less distant part of a folded macromolecule).” https://lnkd.in/dN969hA View in LinkedIn

EVOLUTIVE CHEMISTRY. “The combination of the features of supramolecular systems—information and programmability, dynamics and reversibility, constitution and diversity—leads toward the emergence of adaptive/evolutive chemistry. It is, by essence, of supramolecular nature because it is determined by interaction with an external entity. It may be constitutional and/or morphological (as occurs in “induced fit” for instance). Adaptive chemistry implies selection and growth under time reversibility.” https://lnkd.in/dN969hA View in LinkedIn

ADAPTIVE MATTER. “In the long-range perspective, the development of chemical science is toward complex systems, spanning the broadest outlook from divided to condensed matter then to organized and adaptive matter, on to living matter and thinking matter, up the ladder of complexity.” https://lnkd.in/dN969hA View in LinkedIn

CHEMICAL EMERGENCE. “At each level of increasing complexity novel features emerge that do not exist at lower levels, which are deducible from but not reducible to those of lower levels.” https://lnkd.in/dN969hA View in LinkedIn

NEW DISCIPLINE. “A science of complex matter, of informed, self-organized, evolutive matter.” https://lnkd.in/dN969hA View in LinkedIn

SO ENDS this excerpt on the exciting new thinking about supposedly inert chemicals. The concept of chemical evolution, adaptation and selection helps to bridge the gap in our understanding of the emergence of life from simple chemicals. It is clear that we have underestimated supposedly simple matter, simple chemicals. Nothing is quite what it seems to be. View in LinkedIn

Work of genius. A must watch. https://lnkd.in/dxrn7WJ View in LinkedIn

GENOMICS AND HOLISM. “The tremendous growth of interest in systems biology was driven by the simultaneous rise of genomics, which is the field dedicated to the large-scale analysis of the properties of genomes.” https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn

NEW FIELDS. “The concurrent development of microarrays as the first platform for large-scale gene expression measurements led to the birth of the new field of functional genomics, which quickly expanded to include other biomolecules, namely proteomics and metabolomics for the measurements of protein levels and metabolic intermediates respectively.” https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn

GLOBAL ASSESSMENTS. “A hallmark of this functional data is that they represent global measurements of thousands of molecular features where no one feature has an a priori higher importance than others.” https://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-8-S2-S1 View in LinkedIn