Month: September 2022

"THE GUT MICROBIOME refers to the collection of microorganisms and their genomes in the gut habitat which are now regarded as a critical node in the brain-gut axis.” http://www.sciencedirect.com/science/article/pii/S0166432814004768 View in LinkedIn

BACTERIA-HUMAN CONTROL. "The interactions between commensal microbiota and its host are for the most part beneficial, and the presence of commensal organisms is critical to immune function, nutrient processing, other aspects of host physiology, and to brain development and function." https://lnkd.in/duCKdMh View in LinkedIn

SEROTONIN-BACTERIA INTERFACE. "The vast majority of serotonin, an estimated 95%, is found within the GI tract. Here, 90% of serotonin is localized within epithelial enterochromaffin cells (ECs) and the remaining 10% remains within the ENS. And while serotonin biosynthesis in the brain remains largely independent of the GI tract, serotonin biosynthesis within the GI tract involves specific microbiota–gut interactions." http://onlinelibrary.wiley.com/doi/10.1111/cmi.12585/full View in LinkedIn

SEROTONIN. "Although commensal microbes can produce neuroactive molecules, recent work revealed a microbe–host mechanism of serotonin production. Spore-forming bacteria within the gut microbiota release metabolites, including SCFAs, signalling EC production of serotonin." http://onlinelibrary.wiley.com/doi/10.1111/cmi.12585/full View in LinkedIn

BACTERIA AND MENTAL HEALTH. "The vast majority GI tryptophan is not utilized for serotonin production, but rather metabolized via the kynurenine pathway. Alteration of kynurenine:tryptophan ratios has been linked with depression and anxiety. The gut microbiota may modulate this ratio directly." http://onlinelibrary.wiley.com/doi/10.1111/cmi.12585/full View in LinkedIn

PSYCHOBIOTICS. "While the effects of spore-forming bacteria on mood and behaviour remain unexamined, concurrent studies revealed antidepressant properties of specific gut microbes. Whether spore-forming bacteria belong in the emerging class of “psychobiotics” is yet to be determined." http://onlinelibrary.wiley.com/doi/10.1111/cmi.12585/full View in LinkedIn