Month: September 2022

Victoria to permanently ban fracking and coal seam gas exploration View in LinkedIn

RETROVIRAL ROOTS. "Life could not function without the key agents of DNA replication, namely mRNA, tRNA, and rRNA. Not only rRNA, but also tRNA and the processing of the primary transcript into the pre-mRNA and the mature mRNA are clearly descended from retro-“elements” with obvious retroviral ancestry." (mRNA = messenger RNA; tRNA = transfer RNA; rRNA = ribosomal RNA). https://lnkd.in/euyhznh View in LinkedIn

NON-CODING RNAs. "They seem to be remnants of viral infection events that did not kill their host but transferred phenotypic competences to their host and changed both the genetic identity of the host organism and the identity of the former infectious viral swarms." https://lnkd.in/euyhznh View in LinkedIn

VIRAL GENETIC TOOLS. "Noncoding RNAs may represent a great variety of modular tools for cellular needs that are derived from persistent nonlytic viral settlers." https://lnkd.in/euyhznh View in LinkedIn

PERSISTENT VIRUSES. "Their active role is regulated and depends on the cell cycle of the host in which they are transcribed, replicated, and silenced again during a certain phase of the cell cycle." https://lnkd.in/euyhznh View in LinkedIn

NON-CODING RNA WINDOWS. "Their persistent status is changed into an active role only during a strictly defined phase of the cell cycle in which they are needed for a specialized function and are still competent, most likely being adapted especially for this function. After fulfilling this function they disappear again." https://lnkd.in/euyhznh View in LinkedIn

NON-CODING RNA NEEDS. "To ensure this function and its fine-tuned regulation, they need a highly conserved regulative viral protein domain with characteristic host interactions to use (manipulate) the host replication for their special needs. Their behavioral pattern is adapted to the host and circumvents the acute lytic phase." https://lnkd.in/euyhznh View in LinkedIn

NON-LYTIC LIFESTYLE. "We can find similar reproduction patterns in RNA viruses. Replication of retroviruses in eukaryotes depends on successful entry into the membrane of host cells. Some retroviruses circumvent this active entry of the cellular membrane in that they wait until the start of the cell-cycle phase-dependent dissolution of the cell membrane during replication." https://lnkd.in/euyhznh View in LinkedIn

PERSISTENT RNA RETROVIRUSES. "The overwhelming majority are nonlytic but persistent retroviruses. They infect the host organism and integrate their gag, pol, env functional parts into the host genome and adapt to the replication cycle of the host organism without leaving the host cells." https://lnkd.in/euyhznh View in LinkedIn

PERSISTENT RNA RETROVIRUSES. "In becoming part of the identity of the host genotype they change the genome formation and transfer a phenotype to the host that noninfected host genomes do not possess." https://lnkd.in/euyhznh View in LinkedIn