linkedin post 2017-04-11 05:29:31

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VIRUS TO EUKARYOTIC CELLS. "If DNA and DNA replication proteins originated in viruses, one can imagine that DNA replication mechanisms have been transferred from viruses to cells. Many protein phylogenies support the idea of ancient transfers of replicative proteins between cells and viruses." https://lnkd.in/dNTbYMw View in LinkedIn
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linkedin post 2017-04-13 17:25:18

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VIRAL DNA INSERTED INTO HOST. "The replication cycle of a retrovirus entails the insertion ("integration") of a DNA copy of the viral genome into the nuclear genome of the host cell. Most retroviruses infect somatic cells, but occasional infection of germline cells (cells that produce eggs and sperm) can also occur. The retroviral proteins themselves have (sometimes) been co-opted to serve novel host functions, particularly in reproduction and development. " https://lnkd.in/dwG2wT9 View in LinkedIn
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linkedin post 2017-04-13 06:49:09

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EXOTIC VIRUS PROPERTIES. "Viruses can have exotic properties: they can replicate in dead cells, repair radiation-damaged hosts, or recombine with other dead viruses and generate an intact cell. In some cases, hosts can benefit from viruses. An ancient retrovirus supported the development of the placenta in mammals." https://lnkd.in/eGaw2Kq View in LinkedIn
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linkedin post 2017-04-10 04:43:33

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RANGE OF SOPHISTICATION. "Some DNA viruses replicate their genome using only replication proteins encoded by their host (with the exception of initiator proteins). However, many large DNA viruses encode also several proteins involved in the elongation step of DNA replication." https://lnkd.in/dNTbYMw View in LinkedIn
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linkedin post 2017-04-13 06:46:00

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VIRAL FOSSIL RECORD IS DNA. "The genomes of many organism contain endogenous viral elements (EVEs). These DNA sequences are the remnants of ancient virus genes and genomes that ancestrally 'invaded' the host germline. For example, the genomes of most vertebrate species contain hundreds to thousands of sequences derived from ancient retroviruses." https://lnkd.in/dPyAFVt View in LinkedIn
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